Deception sometimes results in nonconsensual sex. A recent body of literature diagnoses such violations as invalidating consent: the agreement is not morally transformative, which is why the sexual contact is a rights violation. We pursue a different explanation for the wrongs in question: there is valid consent, but it is not consent to the sex act that happened. Semantic conventions play a key role in distinguishing deceptions that result in nonconsensual sex (like stealth condom removal) from those that don’t (like (...) white lies). Our framework is also applicable to more controversial cases, like those implicated in so-called “gender fraud” complaints. (shrink)

Standpoint theorists have long been clear that marginalization does not make better understanding a given. They have been less clear, though, that social dominance does not make ignorance a given. Indeed, many standpoint theorists have implicitly committed themselves to what I call the strong epistemic disadvantage thesis. According to this thesis, there are strong, substantive limits on what the socially dominant can know about oppression that they do not personally experience. I argue that this thesis is not just implausible but (...) politically pernicious; it is an excuse for ignorance and silence that stifles our ability to address many injustices. Moreover, I argue that if we are to avoid lending support to the SEDT while working within a standpoint theory framework, we must hold that the socially dominant can achieve marginalized standpoints. So, we must hold that men can achieve feminist standpoints, that white women (and men) can achieve black feminist standpoints, and so on. (shrink)

The juxtaposition of models of God and Christian faith may seem repugnant to many, as models are tentative and faith aims at an abiding certainty. In fact, for many Christians, using models of God in worship amounts to idolatry. By examining Biblical and extra-Biblical views of idolatry, I argue that models are not idols. To the contrary, the practice of God-modeling inoculates Christians against one of the most seductive idols of our age: the love of certainty. Furthermore, by examining meditations (...) upon certainty in Melville’s Moby Dick and the early discourses of the Buddha, I suggest that overweening conviction is a vice that hinders rather than guarantees Christian discipleship, and that Christian faith is better defined as any or all of the following: relative confidence in propositions, faithful relationship, and a virtue of disciplined credulity. (shrink)

There is an undeniable tendency to dismiss women’s sexual assault allegations out of hand. However, this tendency is not monolithic—allegations that black men have raped white women are often met with deadly seriousness. I argue that contemporary rape culture is characterized by the interplay between rape myths that minimize rape, and myths that catastrophize rape. Together, these two sets of rape myths distort the epistemic resources that people use when assessing rape allegations. These distortions result in the unjust exoneration (...) of people we cannot conceive of as monstrous, while making it too easy to believe that some marginalized people could be rapists. I also argue that rape myths enable a novel kind of epistemic injustice. This injustice concerns how our assessments of trustworthiness and our assessments of plausibility interact. I argue that rape myths can result in runaway credibility deflations that can explain both why people fail to believe most women, and also why people may unjustly believe false allegations that white women have been raped by black men. (shrink)

Frantz Fanon offers a lucid account of his entrance into the white world where the weightiness of the ‘white gaze’ nearly crushed him. In chapter five of Black Skins, White Masks, he develops his historico-racial and epidermal racial schemata as correctives to Merleau-Ponty’s overly inclusive corporeal schema. Experientially aware of the reality of socially constructed (racialized) subjectivities, Fanon uses his schemata to explain the creation, maintenance, and eventual rigidification of white-scripted ‘blackness’. Through a re-telling of his (...) own experiences of racism, Fanon is able to show how a black person in a racialized context eventually internalizes the ‘white gaze’. In this essay I bring Fanon’s insights into conversation with Foucault’s discussion of panoptic surveillance. Although the internalization of the white narrative creates a situation in which external constraints are no longer needed, Fanon highlights both the historical contingency of ‘blackness’ and the ways in which the oppressed can re-narrate their subjectivities. Lastly, I discuss Fanon’s historically attuned ‘new humanism’, once again engaging Fanon and Foucault as dialogue partners. (shrink)

Frederick Douglass, in his first autobiography, Narrative of the Life of Frederick Douglass, describes how his sociopolitical identity was scripted by the white other and how his spatiotemporal existence was likewise constrained through constant surveillance and disciplinary dispositifs. Even so, Douglass was able to assert his humanity through creative acts of resistance. In this essay, I highlight the ways in which Douglass refused to accept the other-imposed narrative, demonstrating with his life the truth of his being—a human being unwilling (...) to be classified as thing or property. As I engage selected passages and key events from Douglass's narrative, I likewise explore the ways in which the resistance tactics. (shrink)

In this paper I begin by explaining what epistemic injustice is and what ordinary language philosophy is. I then go on to ask why we might doubt the usefulness of ordinary language philosophy in examining epistemic injustice. In the first place, we might wonder how ordinary language philosophy can be of use, given that many of the key terms used in discussing epistemic injustice, including ‘epistemic injustice’ itself, are not drawn from our ordinary language. We might also have doubts about (...) the usefulness of ordinary language philosophy in this area, given ordinary language philosophers’ aversion to theory. Finally, we might have doubts about the usefulness of ordinary language philosophy due to the fact that the study of epistemic injustice is clearly a study of practical matters concerning the way the world is and has been historically. If ordinary language philosophy is just concerned with grammar, what use can it be to practical and social philosophy concerning current issues? In response to these worries, I demonstrate the usefulness of ordinary language philosophy in practice by applying the insights of Ludwig Wittgenstein and Alan R. White to a problem that Miranda Fricker raises, but does not answer: about whether there is a confidence condition on knowledge. I also make use of Gilbert Ryle's distinction between ‘the use of ordinary language’ and ‘the ordinary use of an expression’ to show that the terminology used in examining epistemic injustice is ordinary in some sense. (shrink)

Currently, the widely used notion of activity is increasingly present in computer science. However, because this notion is used in specific contexts, it becomes vague. Here, the notion of activity is scrutinized in various contexts and, accordingly, put in perspective. It is discussed through four scientific disciplines: computer science, biology, economics, and epistemology. The definition of activity usually used in simulation is extended to new qualitative and quantitative definitions. In computer science, biology and economics disciplines, the new simulation activity definition (...) is first applied critically. Then, activity is discussed generally. In epistemology, activity is discussed, in a prospective way, as a possible framework in models of human beliefs and knowledge. (shrink)

Shortages of new therapeutics to treat coronavirus disease (COVID-19) have forced clinicians, public health officials, and health systems to grapple with difficult questions about how to fairly allocate potentially life-saving treatments when there are not enough for all patients in need (1). Shortages have occurred with remdesivir, tocilizumab, monoclonal antibodies, and the oral antiviral Paxlovid (2) -/- Ensuring equitable allocation is especially important in light of the disproportionate burden experienced during the COVID-19 pandemic by disadvantaged groups, including Black, Hispanic/Latino and (...) Indigenous communities, individuals with certain disabilities, and low-income persons. However, many health systems have resorted to first-come, first-served approaches to allocation, which tend to disadvantage individuals with barriers in access to care (3). There is mounting evidence of racial, ethnic, and socioeconomic disparities in access to medications for COVID-19 (4, 5). -/- One potential method to promote equitable allocation is to use a weighted lottery, which is an allocation strategy that gives all eligible patients a chance to receive the scarce treatment while also allowing the assignment of higher or lower chances according to other ethical considerations (6). We sought to assess the feasibility of implementing a weighted lottery to allocate scarce COVID-19 medications in a large U.S. health system and to determine whether the weighted lottery promotes equitable allocation. (shrink)

Initial responses to questionnaires used to assess participants' understanding of informed consent for malaria vaccine trials conducted in the United States and Mali were tallied. Total scores were analyzed by age, sex, literacy (if known), and location. Ninety-two percent (92%) of answers by United States participants and 85% of answers by Malian participants were correct. Questions more likely to be answered incorrectly in Mali related to risk, and to the type of vaccine. For adult participants, independent predictors of higher scores (...) were younger age and female sex in the United States, and male sex in Mali. Scores in the United States were higher than in Mali (P = 0.005). Despite this difference participants at both sites were well informed overall. Although interpretation must be qualified because questionnaires were not intended as research tools and were not standardized among sites, these results do not support concerns about systematic low understanding among research participants in developing versus developed countries. (shrink)

Consider an infinite series whose items are each explained by their immediate successor. Does such an infinite explanation explain the whole series or does it leave something to be explained? Hume arguably claimed that it does fully explain the whole series. Leibniz, however, designed a very telling objection against this claim, an objection involving an infinite series of book copies. In this paper, I argue that the Humean claim can, in certain cases, be saved from the Leibnizian “infinite book copies” (...) objection, and that this provides an interesting way to defuse some cosmological arguments for the existence of God and to give a non-theistic but complete explanation of the Universe. In the course of my argumentation, I also show that circular explanations can be “self-explanatory” as well: explaining two items by each other can explain the couple of items tout court. (shrink)

We examine how Frege’s contrast between identity judgments of the forms “a=a” vs. “a=b” would fare in the special case where ‘a’ and ‘b’ are complex mental representations, and ‘a’ stands for an introspected ‘I’-thought. We first argue that the Fregean treatment of I-thoughts entails that they are what we call “one-shot thoughts”: they can only be thought once. This has the surprising consequence that no instance of the “a=a” form of judgment in this specific case comes out true, let (...) alone a priori true. This further reinforces Glezakos’s objections against the set-up of Frege’s puzzle, while also raising what we think is an acute problem for Fregeans, insofar as I-thought (and indexical thinking more generally), understood in their way, turns out to be incompatible with some basic features of rationality. (shrink)

In this article I interpret John Rawls’s concept of the original position as a spiritual exercise. In addition to the standard interpretation of the original position as an expository device to select principles of justice for the fundamental institutions of society, I argue that Rawls also envisages it as a “spiritual exercise”: a voluntary personal practice intended to bring about a transformation of the self. To make this argument, I draw on the work of Pierre Hadot, a philosopher and classicist, (...) who introduced the idea of spiritual exercises as central to ancient and modern conceptions of philosophy. By reading Rawls alongside Hadot, this article portrays Rawls as a thinker deeply concerned with the question of how subjects can lead more just and fulfilling lives. It also proposes that the original position as a spiritual exercise can help defend liberalism as a social and political doctrine. (shrink)

In a previous article on cosmological arguments, I have put forward a few examples of complete infinite and circular explanations, and argued that complete non-wellfounded explanations such as these might explain the present state of the world better than their well-founded theistic counterparts (Billon, 2021). Although my aim was broader, the examples I gave there implied merely causal explanations. In this article, I would like to do three things: • Specify some general informative conditions for complete and incomplete non-wellfounded causal (...) explanations that can be used to assess candidate explanations and to generate new examples of complete non-wellfounded explanations. • Show that these conditions, which concern chains of causal explanations, easily generalize to chains of metaphysical, grounding explanations and even to chains involving other “determination relations” such as supervenience. • Apply these general conditions to the recent debates against the existence of nonwellfounded chains of grounds and show, with a couple of precise examples, that the latter can be complete, and that just like in the case of causal explanations, non-wellfoundedness can in fact be an aset rather than a liability. (shrink)

Motivationally unconscious (M-unconscious) states are unconscious states that can directly motivate a subject’s behavior and whose unconscious character typically results from a form of repression. The basic argument for M-unconscious states claims that they provide the best explanation to some seemingly non rational behaviors, like akrasia, impulsivity or apparent self-deception. This basic argument has been challenged on theoretical, empirical and conceptual grounds. Drawing on recent works on apparent self-deception and on the ‘cognitive unconscious’ I assess those objections. I argue that (...) (i) even if there is a good theoretical argument for its existence, (ii) most empirical vindications of the M-unconscious miss their target. (iii) As for the conceptual objections, they compel us to modify the classical picture of the M-unconscious. I conclude that M-unconscious states and processes must be affective states and processes that the subject really feels and experiences —and which are in this sense conscious— even though they are not, or not well, cognitively accessible to him. Dual process psychology and the literature on cold-hot empathy gaps partly support the existence of such M-unconscious states. (shrink)

What are the identity and persistence conditions of videogames? This paper surveys the contemporary philosophical literature on this topic. Specifically, I discuss various views which attempt to ground the identity of videogame works in their rules, in their algorithmic structure, in their source code, or in contextual parameters surrounding gameplay. While these proposals all have merits of their own, I argue that none of them are satisfactory. My conclusion is therefore negative: we still lack an adequate theoretical model to account (...) for the identity and persistence conditions of videogames. (shrink)

Patients suffering from the Cotard syndrome can deny being alive, having guts, thinking or even existing. They can also complain that the world or time have ceased to exist. In this article, I argue that even though the leading neurocognitive accounts have difficulties meeting that task, we should, and we can, make sense of these bizarre delusions. To that effect, I draw on the close connection between the Cotard syndrome and a more common condition known as depersonalisation. Even though they (...) are not delusional, depersonalised patients seem to have experiences that are quite similar to those of Cotard patients. I argue that these experiences are essentially characterised by a lack of subjective character and of two other structural features of experience, which I call ‘the present character’ and ‘the actual character’. Cotard's nihilistic delusions simply consist in taking these anomalous experiences at face value. (shrink)

It is reasonable to say that the team had efficiently managed its limited resources to overcome the very challenging months before its fifth anniversary (Aug. 1, 2022).

There are two main approaches within classical cognitive science to explaining how humans can entertain mental states that integrate contents across domains. The language-based framework states that this ability arises from higher cognitive domain-specific systems that combine their outputs through the language faculty, whereas the language-independent framework holds that it comes from non-language-involving connections between such systems. This article turns on its head the most influential empirical argument for the language-based framework, an argument that originates from research on spatial reorientation. (...) I make the case that neuroscientific findings about spatial reorientation in rodents and humans bolster the language-independent framework instead. (shrink)

Spelke convincingly argues that we should posit six innate modular systems beyond the periphery (i.e., beyond low-level perception and motor control). I focus on the case of spatial navigation (Ch. 3) to claim that there remain powerful considerations in favor of positing additional innate, nonperipheral modules. This opens the door to stronger forms of nativism and nonperipheral modularism than Spelke's.

Fichte is the first great Post-Kantian Idealist and his debt to Spinozism has been acknowledged by virtually all of his commentators. However, the extent of Spinoza’s influence on Fichte has not been spelled out in much detail. In response to this I propose to do two things. Firstly, I propose to provide a typology of interpretations of Fichte’s Absolute I, as some commentators seem to get entangled in these different interpretations, which can be very confusing to their readership. Secondly, I (...) wish to demonstrate that the Fichtean system is better understood in the light of its Spinozist influences. (shrink)

Descartes was certain that he was thinking and he was accordingly certain that he existed. Like Descartes, we seem to be more certain of our thoughts and our existence than of anything else. What is less clear is the reason why we are thus certain. Philosophers throughout history have provided different interpretations of the cogito, disagreeing both on the kind of thoughts it characterizes and on the reasons for its cogency. According to what we may call the empiricist interpretation of (...) the cogito, I can only claim to be certain of having experiences, and this certainty, as well as that of my own existence, stems from their phenomenal and subjective character. According to rationalist interpretations, on the other hand, I am certain of having some self-reflexive propositional attitudes, and this certainty derives from their rational features. Psychiatric patients suffering from acute forms of depersonalization or of the Cotard syndrome often doubt that they think and exist, and might even believe that they don't. I argue that their study allows us to favor the empiricist interpretation of the cogito. (shrink)

Basic self-awareness is the kind of self-awareness reflected in our standard use of the first-person. Patients suffering from severe forms of depersonalization often feel reluctant to use the first-person and can even, in delusional cases, avoid it altogether, systematically referring to themselves in the third-person. Even though it has been neglected since then, depersonalization has been extensively studied, more than a century ago, and used as probe for understanding the nature and the causal mechanisms of basic self-awareness. In this paper, (...) I argue that depersonalized patients indeed have an impaired basic self-awareness, and that their study allows us both to favor one specific theory of basic self-awareness and to understand what is wrong with its rivals. According to the favored theory, which I call Cartesian, we are basically self-aware in virtue of being acquainted with ourselves through introspection. (shrink)

This is a commentary on Andrea Lavazza and Murilo Vilaça's article "Human Extinction and AI: What We Can Learn from the Ultimate Threat" (Lavazza & Vilaça, 2024). I discuss the potential concern that their proposal to create artificial successors to "insure" against the tragedy of human extinction might mean being too quick to accept that catastrophic prospect as inevitable, rather than single-mindedly focusing on avoiding it. I also consider the question of the value that we might reasonably assign to such (...) a future of artificial successors under the assumption that they do not enjoy phenomenal consciousness. (shrink)

Patients suffering from depersonalization complain of feeling detached from their body, their mental states, and actions or even from themselves. In this chapter, I argue that depersonalization consists in the lack of a phenomenal feature that marks my experiences as mine, which is usually called “mineness,” and that the study of depersonalization constitutes a neglected yet incomparable probe to assess empirically the scope, role, and even the nature of mineness. Here is how I will proceed. After describing depersonalization (§2) and (...) arguing that it involves a lack of mineness (§3) I will confront a series of objections (§4). I will then spell out what depersonalization can teach us about the scope of mineness (§5), about its role and psychological function (§6) and even about its nature (§7). (shrink)

Sau 14 tháng bền bỉ, phương pháp đổi mới việc rà soát tổng quan lý thuyết xã hội của ISR, dựa trên dữ liệu metadata có cấu trúc, đã được xuất bản bởi tạp chí MethodsX (Elsevier Q2 SCImago | ISI Web of Science). Bài có tiêu đề: “Making social sciences more scientific” [1].

All disciplines must define their basic units and core processes. In evolutionary biology, the core process is natural selection and the basic unit of selection and adaptation is the individual. To operationalize the theory of natural selection we must count individuals, as they are the bearers of fitness. While canonical individuals have often been taken to be multicellular organisms, the hierarchy of life shows that new kinds of individuals have evolved. A variety of criteria have been used to define biological (...) individuality. Some criteria rely on the presence/absence of a particular property while others advocate an approach that reflects the process of natural selection. The plethora of approaches to classifying individuality has resulted in confusion regarding how to study individuality in a given taxon. (shrink)

Many philosophers regard the persistence of philosophical disputes as symptomatic of overly ambitious, ill-founded intellectual projects. There are indeed strong reasons to believe that persistent disputes in philosophy (and more generally in the discourse at large) are pointless. We call this the pessimistic view of the nature of philosophical disputes. In order to respond to the pessimistic view, we articulate the supporting reasons and provide a precise formulation in terms of the idea that the best explanation of persistent disputes entails (...) that they are pointless. We then show how to answer the pessimistic argument. Taking a well-known mathematical controversy as our paradigm example, we argue that some persistent disputes reflect substantive disagreements at the “meta-analytic” level, i.e., disagreements about the best way, among quite different candidates, to understand the topic at issue, and the best associated cluster of analytic truths one should accept concerning it. Moreover, our concrete example shows that such meta-analytic disagreements can in principle be settled and yield a genuine theoretical (as opposed to merely pragmatic) breakthrough. We conclude optimistically that persistent disputes can be an important means of fostering epistemic progress. (shrink)

How should we respond to the humanity of others? Should we care for others’ well-being? Respect them as autonomous agents? Largely neglected is an answer we can find in the religious traditions of Judaism, Christianity and Buddhism: we should love all. This paper argues that an ideal of love for all can be understood apart from its more typical religious contexts and moreover provides a unified and illuminating account of the the nature and grounds of morality. I defend a novel (...) account of love for all that avoids serious worries about the incoherence or impossibility of loving everyone. Doing so requires countenancing a neglected form of love. Love admits as its object not just individual entities like people and groups; we can also bear a love for the Fs in general---for all the Joneses, all the philosophers, or even all the human beings. I go on to argue that while it is possible for ordinary agents like us to love all, we shouldn't. Instead, we should approximate love for all. The minimal approximation of love for all is, surprisingly, respect; I derive the basic, structural features of deontological ethics (including anti-paternalism and anti-aggregation) from the ideal of loving all. (NB: This paper used to be titled "Ethics in the Shadow of Love" and has been cited as an unpublished manuscript under that title.). (shrink)

Most paradoxes of self-reference have a dual or ‘hypodox’. The Liar paradox (Lr = ‘Lr is false’) has the Truth-Teller (Tt = ‘Tt is true’). Russell’s paradox, which involves the set of sets that are not self-membered, has a dual involving the set of sets which are self-membered, etc. It is widely believed that these duals are not paradoxical or at least not as paradoxical as the paradoxes of which they are duals. In this paper, I argue that some paradox’s (...) duals or hypodoxes are as paradoxical as the paradoxes of which they are duals, and that they raise neglected and interestingly different problems. I first focus on Richard’s paradox (arguably the simplest case of a paradoxical dual), showing both that its dual is as paradoxical as Richard’s paradox itself, and that the classical, Richard-Poincaré solution to the latter does not generalize to the former in any obvious way. I then argue that my argument applies mutatis mutandis to other paradoxes of self-reference as well, the dual of the Liar (the Truth-Teller) proving paradoxical. (shrink)

Open Peer Commentary on P. Zawadzki and A. K. Adamczyk's target article in AJOB Neuroscience on the potential of optogenetics for memory modification. I argue for a radically pluralistic understanding of the notion of authenticity, and highlight the need to further clarify the specific nature of the authors' concern about authenticity, as well as its policy implications.

This paper considers the medium of videogames from a goodmanian standpoint. After some preliminary clarifications and definitions, I examine the ontological status of videogames. Against several existing accounts, I hold that what grounds their identity qua work types is code. The rest of the paper is dedicated to the epistemology of videogaming. Drawing on Nelson Goodman and Catherine Elgin's works, I suggest that the best model to defend videogame cognitivism appeals to the notion of understanding.

Many species rely on the three-dimensional surface layout of an environment to find a desired goal following disorientation. They generally do so to the exclusion of other important spatial cues. Two influential frameworks for explaining that phenomenon are provided by geometric-module theories and view-matching theories of reorientation respectively. The former posit a module that operates only on representations of the global geo- metry of three-dimensional surfaces to guide behavior. The latter place snapshots, stored representations of the subject’s two-dimensional retinal stimulation (...) at specific locations, at the heart of their accounts. In this paper, I take a fresh look at the debate between them. I begin by making a case that the empirical evidence we currently have does not clearly favor one framework over the other, and that the debate has reached something of an impasse. Then, I present a new explanatory problem—the representation selection problem—that offers the pro- spect of breaking the impasse by introducing a new type of explanatory consideration that both frameworks must address. The representation selection problem requires explaining how subjects can reliably select the relevant representation with which they initiate the reorientation process. I argue that the view-matching framework does not have the resources to address this problem, while a certain type of theory within the geometric-module framework can provide a natural response to it. In showing this, I develop a new geometric-module theory. (shrink)

If I see, hear, or touch a sparrow, the sparrow seems real to me. Unlike Bigfoot or Santa Claus, it seems to exist; I will therefore judge that it does indeed exist. The “sense of existence” refers to the kind of awareness that typically grounds such ordinary judgments of existence or “reality.” The sense of existence has been invoked by Humeans, Kantians, Ideologists, and the phenomenological tradition to make substantial philosophical claims. However, it is extremely controversial; its very existence has (...) been called into question. This paper aims to clarify the nature and reality of the sense of existence by studying a psychiatric condition in which the sense appears to be disrupted: depersonalization disorder (DPD). (shrink)

Automated influence is one of the most pervasive applications of artificial intelligence in our day-to-day lives, yet a thoroughgoing account of its associated individual and societal harms is lacking. By far the most widespread, compelling, and intuitive account of the harms associated with automated influence follows what I call the control argument. This argument suggests that users are persuaded, manipulated, and influenced by automated influence in a way that they have little or no control over. Based on evidence about the (...) effectiveness of targeted advertising as well as empirical results about the nature of attentional control, I provide reasons to reject this argument. In turn, I use C. Thi Nguyen’s theory of value collapse to develop a new account of the harmfulness of automated influence. (shrink)

The enhancement of athletic performance using procedures that increase physical ability, such as anabolic steroids, is a familiar phenomenon. Yet recent years have also witnessed the rise of direct interventions into the brain, referred to as “neuro-doping”, that promise to also enhance sports performance. This paper discusses one potential objection to neuro-doping, based on the contribution to athletic achievement, particularly within endurance sports, of effortfully overcoming inner challenges. After introducing the practice of neuro-doping, and the controversies surrounding it, I describe (...) two major mechanisms some have proposed to explain how it might produce its putative performance-enhancing effects. I then clarify the notion of effort, and its relationship to neuro-doping. I also briefly address common concerns about access and safety. My central argument invokes considerations of effort to maintain that we have at least a significant reason for prohibiting the use of neuro-doping in officially regulated endurance competitions – though only conditional upon a specific set of empirical assumptions. I consider three possible objections: that neuro-doping is no different from widely accepted enhancement methods, that it can make athletic competition fairer, and that a broader range of factors can compensate for a reduced scope for effort than I recognize. I ultimately conclude that these objections do not refute the argument from effort, while stressing nonetheless that this argument applies more clearly to hypothetical improved forms of neuro-doping than to existing ones, and is not meant to offer a final overall verdict on how neuro-doping should be regulated. (shrink)

The Adverse Outcome Pathway (AOP) concept is a knowledge assembly and communication tool to facilitate the transparent translation of mechanistic information into outcomes meaningful to the regulatory assessment of chemicals. The AOP framework and associated knowledgebases (KBs) have received significant attention and use in the regulatory toxicology community. However, it is increasingly apparent that the potential stakeholder community for the AOP concept and AOP KBs is broader than scientists and regulators directly involved in chemical safety assessment. In this paper we (...) identify and describe those stakeholders who currently—or in the future—could benefit from the application of the AOP framework and knowledge to specific problems. We also summarize the challenges faced in implementing pathway-based approaches such as the AOP framework in biological sciences, and provide a series of recommendations to meet critical needs to ensure further progression of the framework as a useful, sustainable and dependable tool supporting assessments of both human health and the environment. Although the AOP concept has the potential to significantly impact the organization and interpretation of biological information in a variety of disciplines/applications, this promise can only be fully realized through the active engagement of, and input from multiple stakeholders, requiring multi-pronged substantive long-term planning and strategies. (shrink)

Automated influence is one of the most pervasive applications of artificial intelligence in our day-to-day lives, yet a thoroughgoing account of its associated individual and societal harms is lacking. By far the most widespread, compelling, and intuitive account of the harms associated with automated influence follows what I call the control argument. This argument suggests that users are persuaded, manipulated, and influenced by automated influence in a way that they have little or no control over. Based on evidence about the (...) effectiveness of targeted advertising as well as empirical results about the nature of attentional control, I provide reasons to reject this argument. In turn, I use C. Thi Nguyen's theory of value collapse to develop a new account of the harmfulness of automated influence. (shrink)

According to David Chalmers, the virtual entities found in Virtual Reality (VR) and Augmented Reality (AR) environments instantiate virtual properties of a specific kind. It has recently been objected that such a view (i) can’t extend to all types of properties; (ii) leads to a proliferation of property-types; (iii) implausibly ascribes massive errors to VR and AR users; and (iv) faces an analogue of Jackson’s “many-property problem”. My first objective here is to show that advocates of virtual properties can deal (...) with each of these objections. The other goal of this paper is to examine the consequences of Chalmers’ theory in the particular case of AR. If we countenance virtual properties, AR highlights that non-virtual objects can possess both non-virtual and virtual properties. With AR, it also appears that a same non-virtual object can have different and even incompatible properties across augmented environments. Lastly, considering properties in light of AR highlights the risk of an “augmented solipsism”, and calls forth interesting questions about the persistence conditions of non-virtual objects in AR environments. (shrink)

Este artigo pretende mostrar que e como ocorrem, na Doutrina da virtude de Kant, problemas relativos aosentido e referência dos juízos e conceitos fundamentais dessa obra, isto é, problemas semânticos. Tendo em vistaesse fim, explicitaremos de forma breve o desenvolvimento dessa problemática na filosofia prática de Kant e, em seguida, realizaremos a análise da Doutrina da virtude a partir do ponto de vistasemântico, a fim de identificar os mencionados problemas e as soluções fornecidas por Kant para estes problemas. -/- This (...) paper intends to show what and how problems related to the sense and reference of the fundamental judgments and concepts in Kant's Doctrine of virtue happen, that is, semantic problems. In order to perform this end, I shortly make explicit the development of this problematic in Kant's practical philosophy and, soon after, we will accomplish the analysis of the Doctrine of virtue from the semantic point of view, in order to identify the mentioned problems and the solutions supplied by Kant for these problems. (shrink)

There is a long tradition in philosophy of blaming passions for our unhappiness. If only we were more rational, it is claimed, we would live happier lives. I argue that such optimism is misguided and that, paradoxically, people with desires, like us, cannot be both happy and rational. More precisely, if someone rational has desires he will not be fully happy, and if he has some desires that are rational and – in a yet-to-be-specified sense – demanding, he will be (...) frankly unhappy. Call this claim Rational Pessimism. The argument for Rational Pessimism can be considered as a variation on a Schopenhauerian argument that bluntly claims that, because desires involve lack and suffering, desiring souls like us cannot be happy. I argue that, even if Schopenhauer’s argument escapes most attacks that have been targeted against it, it faces decisive empirical objections. I argue that Schopenhauer’s argument can, however, be rescued if it is assumed that we are rational. (shrink)

In this paper, I will look at the relationship between Weitz’s claim that art is an “open” concept and Dickie’s institutional theory of art, in its most recent form. Dickie’s theory has been extensively discussed, and often criticized, in the literature on aesthetics, yet it has rarely been observed – to my knowledge at least – that the fact that his theory actually incorporates, at least to some extent, Weitz’s claim about the “openness” of the concept of art, precisely accounts (...) for what I take to be the main flaws in the theory. In what follows I present arguments for that claim, looking briefly at the position of both authors with respect to the concept of art, then showing how they relate to each other, and what implications this has for Dickie’s institutional theory, and more generally for the traditional project of characterising art. (shrink)

This paper advocates a new reading of Nelson Goodman’s new riddle of induction. According to Ian Hacking, this famous problem conveys a “pure nominalism”, as it grounds Goodman’s denial regarding the existence of natural kinds. While this interpretation is somewhat convincing, it suffers the major flaw of not corresponding to what Goodman himself understood by “nominalism”. Nominalism, in a goodmanian sense, is indeed primarily a technical demand, which stems from the so-called “calculus of individuals”. I argue that this mereological definition (...) of nominalism allows to understand the new riddle of induction afresh. As a result, Goodman’s riddle is “hyper-nominalist”, i.e., nominalist in a distinct and stronger sense than what Hacking suggested. (shrink)

In this paper, I examine Nelson Goodman’s pluriworldism, understood as the claim that there exists a plurality of actual worlds. This proposal has generally been quickly dismissed in the philosophical literature. I argue that we ought to take it more seriously. As I show, many of the prima facie objections to pluriworldism may receive straightforward answers. I also examine in detail Goodman’s argument for the conclusion that there are many worlds and attempt to show how it might be supported. Eventually, (...) I discuss some underexplored challenges to pluriworldism. (shrink)

New trends in the economic systems management in the context of modern global challenges: collective monograph / scientific edited by M. Bezpartochnyi, in 2 Vol. // VUZF University of Finance, Business and Entrepreneurship. – Sofia: VUZF Publishing House “St. Grigorii Bogoslov”, 2020. – Vol. 1. – 309 p.

It is a common experience to be surprised by an artwork. In this paper, I examine how and why this obvious fact matters for philosophical aesthetics. Following recent works in psychology and philosophers such as Davidson or Scheffler, we will see that surprise qualifies as an emotion of a special kind, essentially “cognitive” or “epistemic” in its nature and functioning. After some preliminary considerations, I wish to hold two general claims: the first one will be that surprise is somehow related (...) to aesthetic appreciation, because it is often the ground to judge of a work’s value. The second point will be that a functional analysis of surprise provides support for cognitivist accounts of aesthetics. If this picture is right, surprise would generally play an important part in aesthetic experience and should also be seen as a paradigm to study the cognitive powers of art. (shrink)

RESUMO Os cuidados para atender às necessidades específicas da fêmea gestante são indispensáveis para o sucesso no manejo reprodutivo de qualquer espécie. Entretanto, é necessário entender que podem acontecer problemas em qualquer uma das fases reprodutivas, inclusive na gestação. Antes de tudo, na clínica e na produção, a sobrevivência dos fetos significa êxito no manejo reprodutivo. Durante o período gestacional podem se desenvolver diversas afecções no útero da fêmea, dentre elas podem ser citadas: mumificação fetal, gravidez ectópica, maceração fetal, prenhez (...) múltipla patológica e diversas anomalias que podem acometer os envoltórios e líquidos fetais. Essas doenças representam prognóstico ruim para a fêmea e para o feto, podendo resultar em perdas fetais. O conhecimento acerca das características dessas afecções, bem como a fisiopatologia e diagnóstico são indispensáveis para o sucesso da reprodução animal. Palavras-chave: Ginecologia, reprodução, gestação. ABSTRACT Care to meet the specific needs of pregnant females is essential for the successful reproductive management of any species. However, it is necessary to understand that problems may occur in any of the reproductive stages, including pregnancy. First of all, in the clinic and production, the survival of fetuses means success in reproductive management. During the gestational period, several pathological conditions can develop in the female uterus, among them fetal mummification, ectopic pregnancy, fetal maceration, pathological multiple pregnancy, and the various anomalies that can affect fetal envelopes and fluids. These illnesses represent a poor prognosis for the female and the fetus and may result in fetal loss. Knowledge about the characteristics of these conditions, as well as the pathophysiology and diagnosis are essential for the success of animal reproduction. Keywords: Gynecology, reproduction, gestation. -/- INTRODUÇÃO Na fisiologia da reprodução nos mamíferos, a implantação e a placentação são processos essenciais na nutrição do embrião e do feto e do seu desenvolvimento. Nos bovinos leiteiros, estima-se uma taxa de fertilização de 95%, com apenas 55% desses zigotos se desenvolvendo a termo e com perda de gestações de 35% (SILVA, 2021). Em equinos varia entre 5 e 15% (BRINSKO et al., 2011) e em suínos chega a 40% (VAN DER LENDE et al., 1994). A reprodução permite a manutenção do equilíbrio biótico, entretanto, falhas podem ocorrer, desde a concepção até o parto, incapacitando o pleno desenvolvimento gestacional e acarretando danos à cadeia produtiva (BRAGA e BARROSO, 2014). A taxa de perda gestacional atinge o pico durante o desenvolvimento embrionário e diminui após 45 dias, à medida que a gestação progride e a placentação ativa está completa (REESE et al., 2020). A placenta permite contato vascular eficaz entre as membranas fetais e o endométrio materno, através do qual ocorre a troca de oxigênio e de nutrientes vindos pelo sangue materno, além dos produtos de excreção do sangue fetal. Ela apresenta quatro membranas: a) âmnio, que contém o fluido amniótico que banha o embrião; b) saco vitelínico, que armazena os nutrientes; c) saco alantoide, onde os restos do metabolismo embrionário são estocados e d) córion, que delimita os limites do embrião e interage seletivamente com o ambiente externo, permitindo nutrientes e/ou oxigênio cheguem ao embrião (SILVA, 2020). No aparelho reprodutivo feminino as estruturas internas são presas pelo ligamento mesovário, que sustenta o ovário; o mesossalpinge, que ancora o oviduto e o mesométrio, que mantém o útero no seu lugar. Ele compreende os ovários, tubas, útero, cérvix, vagina, vestíbulo e vulva (KÖNIG e LIEBICH, 2021). O útero é formado por dois cornos, na região mesogástrica, que formam o corpo uterino, dorsal a vesícula urinária e ventral ao cólon descendente (PINTO e LORIGADOS, 2015). A cérvix fica na região caudal do útero (DYCE, 2019) e é composta pelo óstio uterino interno e o externo (KÖNIG e LIEBICH, 2021). O líquido amniótico é um complexo biológico que proporciona proteção mecânica, nutrientes e substâncias para o crescimento fetal e possui efeito antimicrobiano (UNDERWOOD et al., 2005). Ele desempenha várias funções: protege o feto contra traumas, desidratação e mudanças de temperatura; permite o desenvolvimento fetal e sua mobilidade; amplia a lubrificação da vagina após a ruptura da bolsa, inibe o crescimento bacteriano por ação mecânica de limpeza e previne aderências (GRUNERT e BIRGEL, 1984). As enfermidades do trato reprodutivo têm causado problemas reprodutivos, acarretando perdas econômicas (JÚNIOR et al., 2009). Os problemas na esfera da fisiopatologia da reprodução em animais, está associada ao período do periparto (SCOTT, 2005). Entretanto, existem relatos de sua ocorrência em fêmeas não gestantes e também fora do período puerperal (PRESTES et al., 2008; SALES et al., 2011). Devido à importância das diversas patologias que atingem o útero gravídico, esse trabalho tem como objetivo buscar identificar na literatura científica existente as características, diagnóstico e tratamento de cada alteração uterina, pautando discussão crítica sobre os processos de formação de cada uma. (shrink)

In this paper, I show that, in a number of publications in the early 1950s, Margaret Macdonald argues that art does not admit of definition, that art is—in the sense associated with Wittgenstein—a family resemblance concept, and that definitions of art are best understood as confused or poorly expressed contributions to art criticism. This package of views is most typically associated with a famous paper by Morris Weitz from 1956. I demonstrate that Macdonald advanced that package prior to Weitz, indeed, (...) prior to any other philosopher of art of the period. Despite this, Macdonald’s contribution is nowhere to be found in the subsequent literature on the definition of art. In closing, I raise the prospect that Macdonald was in fact the primary influence on the development of Weitz’s critique of the definitional project. (shrink)

In recent years, philosophers have identified a number of moral and psychological harms associated with the attention economy (Alysworth & Castro, 2021; Castro & Pham, 2020; Williams, 2018). Missing from many of these accounts of the attention economy, however, is what exactly attention is. As a result of this neglect of the cognitive science of attention, many of these accounts are not empirically credible. They rely on oversimplified and unsophisticated accounts of not only attention, but self- control, and addiction as (...) well. Of note are accounts of the attention economy that rely on the ‘brain disease’ rhetoric of addiction and subsequent control failures (Aylsworth & Castro, 2021; Bhargava & Velasquez, 2021), accounts that rely on a strict dichotomy of top-down vs. bottom-up attention (Williams, 2018; Aylsworth & Castro, 2021), and accounts that construe attention as a limited resource (Williams, 2018). -/- Drawing on recent work from the neuroscience and psychology of attention, I demonstrate the shortcomings of these accounts and sketch a way forward for an empirically grounded account of the attention economy. These accounts tend to uphold strict dichotomies of voluntary control (e.g., compulsion versus choice, dual-process models of self-control, and top-down versus bottom-up) that cannot account for the complexities of attentional control, mental agency, and decision-making. As such, these empirically and conceptually impoverished accounts cannot adequately address the current so-called crisis of attention. To better understand the harms associated with the attention economy, we need an empirically responsible account of the nature and function of attention and mental agency. (shrink)

This commentary further explores some of the ethical issues raised by Prof. Peter Singer in his Lanson Lecture “Pandemic Ethics: Five Lessons”. In the first part, I distinguish a prioritarian approach to the allocation of scarce medical resources, from the utilitarian one advocated by Singer. I suggest that the prioritarian view better matches common intuitions about fair distribution, even though it likely needs to be balanced with other principles if it is to have plausibility in contexts like vaccine allocation. In (...) the second part of the commentary, I take a global perspective (as Singer himself does regarding the ethics of lockdowns), and highlight the controversial implications of adopting a fully cosmopolitan ethical outlook when deciding how to distribute Covid-19 vaccines. I also raise justice-related concerns about Singer’s proposal to use well-being as a single metric for evaluating public health policies. (shrink)